Department of Psychology
Department of Psychology

Neuroscience: Dr. Thomas Hnasko, "Dopamine/Glutamate Co-release: Role in Reward Seeking and Cell Death"

Mon, November 11, 2019 | NHB 1.720

3:00 PM

Department of Neuroscience
Seminar Series Fall 2019

 
Thomas Hnasko, PhD
Department of Neurosciences
University of California, San Diego
 

“Dopamine/Glutamate Co-release: Role in Reward Seeking and Cell Death”


Monday, November 11
NHB 1.720, 3pm

 

Hosted by Lauren Dobbs

 See website

 

Abstract: It is now well established that populations of neurons throughout the brain release more than one classical recycling neurotransmitter. This allows presynaptic neurons additional degrees of freedom to signal across multiple domains in space and time. However, little is known of the mechanisms that regulate co-transmission or how co-transmission influences circuit function, animal behavior, or disease. This seminar will describe recent work and new theories on the consequences of co-transmission from midbrain cell groups classically associated with dopamine neurons. Including how glutamate co-release from dopamine neurons has important consequences on selective dopamine neuron vulnerability that could impact Parkinson’s disease pathogenesis. And how GABA and glutamate co-transmission from neurons in the ventral tegmental area can signal reward and drive behavioral reinforcement through mechanisms distinct from dopamine.

 

Sponsored by: Department of Psychology Neuroscience Area

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